Apenas sobre o NModbus (RTU)

using Modbus.Device;
using System;
using System.Collections.Generic;
using System.IO.Ports;
using System.Linq;
using System.Text;
using System.Threading.Tasks;

namespace Modbus
{
    class Program
    {
        static void Main(string[] args)
        {
            SerialPort serialPort = new SerialPort(); //Create a new SerialPort object.
            serialPort.PortName = "COM1";
            serialPort.BaudRate = 9600;
            serialPort.DataBits = 8;
            serialPort.Parity = Parity.None;
            serialPort.StopBits = StopBits.One;
            serialPort.Open();
            ModbusSerialMaster master = ModbusSerialMaster.CreateRtu(serialPort);

            byte slaveID = 1;
            ushort startAddress = 0;
            ushort numOfPoints = 1;
            ushort[] holding_register = master.ReadHoldingRegisters(slaveID, startAddress,
            numOfPoints);
            Console.WriteLine(holding_register);
            Console.ReadKey();
        }
    }
}